2,2'-DITHIOSALICYLIC ACID

PRODUCT IDENTIFICATION
CAS NO. 119-80-2

2,2'-DITHIOSALICYLIC ACID

EINECS NO. 204-352-8
FORMULA S2(C6H4CO2H)2
MOL WT. 306.36

H.S. CODE

 

TOXICITY

  
SYNONYMS 2,2'-Dithiodibenzoic acid; 2-Carboxy-phenyl disulfide;
Bis(2-carboxy-phenyl) disulfide; Dithio-salicylic acid; ,2'-Dithiobis(benzoic acid); 2,2'-Dithiodibenzoesaeure; Bis(o-carboxyphenyl) disulfide; 2,2'-Dithiodibenzoesäure   (German); ácido 2,2'-ditiodibenzoico (Spanish); Acide 2,2'-dithiodibenzoïque (French);
SMILES Phthalic Anhydride, Sulfurdioxide, Disulphide

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE off white to light yellow powder
MELTING POINT 288 - 293 C
BOILING POINT  
SPECIFIC GRAVITY

 

SOLUBILITY IN WATER insoluble

SOLVENT SOLUBILITY

 soluble in alcohol, ether, alkaline solution
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS  

REFRACTIVE INDEX

  
FLASH POINT

 

STABILITY

Stable under ordinary conditions

APPLICATIONS
Salicylic Acid is a white crystalline powder or needle-shaped crystals with sweetish taste; soluble in acetone, ether, alcohol, boiling water, benzene and turpentine, sparingly soluble in chloroformbenzene, slightly soluble in water; melts at 158°C. The sodium salt form (sodium salicylate) is common commercially, prepared from mainly sodium phenolate with carbon dioxide under heating and pressure. It contains both a hydroxyl and a carboxyl group, which react with either an acid or an alcohol. The carboxyl group forms esters with alcohols; e.g. methyl salicylate is formed with methanol, which used in food flavorings and preservatives; menthyl salicylate is formed with methanol, which is used in suntan lotions. The hydroxyl group reacts with acetic acid to form acetylsalicylic acid (called aspirin) which is the most widely common antiseptic and antipyretic agent. Phenyl salicylate (called salol) is formed with phenol, which is also used as an antiseptic and antipyretic agent. The sodium salt (Sodium salicylate), a shiny white powder, is used for antiseptics preparations and as a preservative. In addition to its analgesic and antipyretic properties, salicylic acid possesses keratinolytic properties and fungicidal properties. It ans its derivatives are used in the treatment of hyperkeratotic, dandruff, ichthyosis and psoriasis as well as in the treatment of fungal skin infections such as tinea. Para-Aminosalicylic acid (abbreviated PAS and PASA) is an analogue of para-aminobenzoic acid (abbreviated PABA) that inhibits folic acid synthesis in Mycobacterium tuberculosis and is bacteriostatic, inhibits growth and multiplication of the tubercle bacillus. Para-Aminosalicylic acid and its sodium salt (sodium p-Aminosalicylate) are bacteriostatic against mycobacteria and used in the treatment of tuberculosis; administered orally. Brand names are Tubasal, Nemasol Sodium and etc. Aminosalicylic acids are pharmaceutically active ingredients including anti-infectives against colds, flu, or other virus infections. Mesalamine (5-aminosalicylic acid, abbreviated 5-ASA) an active metabolite of sulfasalazine, used to treat inflammation of the rectum and lower colon, mild to moderate ulcerative colitis proctosigmoiditis, and proctitis. Para-Aminosalicylic acid (4-hydroxybenzoic acid) is used as an intermediate of bacteriostatic agent specially for parabens (alkyl esters of p-hydroxy benzoic acid) which used in food and personal care products as a preservative. It is applied in the production of liquid crystal polymers. It is also used as an intermediate of dyes, insecticides, pharmaceutical, pesticides and other chemical compounds. Salicylic Acid and its derivatives are important for the preparation of other pharmaceutical products, dyes, flavours, and preservatives. 2,2'-Dithiosalicylic Acid is used as an intermediate for the synthesis of pharmaceuticals, dyes, photochemicals (thioxanthones) and biocides (proxel).
SALES SPECIFICATION

APPEARANCE

 off white to light yellow powder

ASSAY

 95.0 % min
MELTING POINT 287 - 293 C

MOISTURE

1.0% max

BENZOIC ACID

1.0% max

AMINO BENZOIC ACID

1.0% max

LOSS ON DRYING

1.0% max
TRANSPORTATION
PACKING
20kgs in bag
HAZARD CLASS  
UN NO.  
OTHER INFORMATION

Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety Phrases: 26-36